Colorectal cancer CRC is the second most common cancer in females and the third in males worldwide. Conventional therapy of CRC is limited by severe side effects and by the development of resistance. Therefore, additional therapies are needed in order to combat the problem of selectivity and drug resistance in CRC patients. Inula viscosa IV is a well-known medicinal perennial herb in traditional medicine. It is used for different therapeutic purposes, such as; topical anti-inflammatic, diuretic, hemostatic, antiseptic, antiphlogistic, and in the treatment of diabetes.

Author:Voodoorg Kazrakus
Language:English (Spanish)
Published (Last):25 August 2016
PDF File Size:13.24 Mb
ePub File Size:12.11 Mb
Price:Free* [*Free Regsitration Required]

Directory of Open Access Journals Sweden. Full Text Available I. In this study, cytotoxic and genotoxic effects of I. Onion bulbs were exposed to 2. The test concentrations have been determined according to doses which are recommended for use in alternative medicine.

There has been statistically significant P viscosa leaf extract induces the total number of chromosomal aberrations and micronuclei MNC formations in A. Also, this paper shows for the first time the induction of cell death, ghost cells, cells with membrane damage, and binucleated cells by extract treatment. These results suggest the cytotoxic and genotoxic effects of the I.

Antioxidant activities and total phenol content of Inula viscosa extracts selected from three regions of Morocco. Conclusions: Our results of antioxidant assays were justified and partially supported the popular usage of the tested plants. The high antioxidant activity found in the plant from Sefrou and its great biomass in this region suggested that Inula viscosa is a good source of natural antioxidants compounds which might have benefits for health.

Full Text Available The antiproliferative and antimicrobial effects of thirteen compounds isolated from Inula viscosa L. The antiproliferative activity was tested against three cell lines using the MTT assay. The microdilution method was used to study the antimicrobial activity against two Gram positive bacteria, two Gram negative bacteria and one fungus. Scanning electron microscopy was used to study the morphological changes in treated cancer cells and bacteria.

Both compounds exert their antiproliferative effect by inducing apoptosis as indicted by the presence of DNA fragmentation, nuclear condensation, and formation of apoptotic bodies in treated cancer cells. Methylated quercetins isolated from Inula viscosa have improved anticancer and antimicrobial properties compared with other flavonoids and are promising as potential anticancer and antimicrobial agents. Analysis of the chemical composition of essential oil from Algerian Inula viscosa L.

The major components for hydrodistillation were: carboxyeudesma-3,11 13 diene Full Text Available With the emergence of multidrug-resistant organisms, combining medicinal plants with synthetic medicines against resistant bacteria becomes necessary. In this study, Synergism between plant extracts methanolic extract and essential oils of Inula viscosa and Anacyclus valentinus and two commonly used antibiotics gentamycin, oxacillin were investigated on three bacterian strains E.

In the first time, the antibacterial effect of extracts alone was tested against 7 strains by disc diffusion and microdilution methods. The minimum inhibitory concentrations of methanolic extracts ranged between 6.

Greuter Leaf Extracts. Full Text Available The small amount of data regarding the antifungal activity of Dittrichia viscosa L.

Greuter against dermatophytes, Malassezia spp. The antibacterial, anti-Candida and anti-Malassezia activities were evaluated by using the disk diffusion method, whereas the anti-Microsporum canis and anti-Aspergillus fumigatus activities were assessed by studying the toxicity effect of the extracts on vegetative growth, sporulation and germination.

All extracts showed an excellent inhibitory effect against bacteria and Candida spp. The results clearly showed that all extracts, in particular the methanolic extract, might be excellent antimicrobial drugs for treating infections that are life threatening i. Effect of ionizing radiation on antioxidants and antibacterial activities of Inula Viscasa.

In the present study, the irradiation processing of Tunisian Inula Viscosa samples was carried out at dose of 5 kGy. The 1,1-diphenylpicrylhydrazyl DPPH free radical-scavenging activity, the azinobis ethylbenzothiazoline 6-sulphonic acid ABTS Ferric reducing antioxidant power FRAP assay and the antibacterial activities of both control and irradiated samples extracted in methanol and ethanol were evaluated.

The results showed that the irr Tunisian Inula Viscosa extracts had strong antioxidant ability. In addition, all extracts were effective against all the gram positive and gram negative pathogens. These data indicated the potential use of gamma-irradiation as a safe technique for preservation of Inula Viscosa as a medicinal plant with effective antioxidant and antibacterial activities. May 1, The purpose An over-night culture of bacteria was adjusted to turbidity equal to 0.

Fitotossine di Inula viscosa per il controllo di piante parassite. Le piante parassite sono incapaci di sintetizzare dagli elementi minerali e nutritivi materiali sufficienti per la loro crescita e sopperiscono a questa deficienza fisiologica utilizzando le sostanze elaborate dalle piante ospiti, che di conseguenza manifestano generalmente una crescita ridotta.

Diverse strategie The genus Inula and their metabolites: from ethnopharmacological to medicinal uses. Although a total of sixteen Inula species were reported in the literature to have ethnopharmacological applications, the species Inula cappa Buch.

Don DC. Aiton [actually the accepted name is Dittrichia viscosa L. Greuter], Inula helenium, Inula britannica L. They are used to treat a large spectrum of disorders, mainly respiratory, digestive, inflammatory, dermatological, cancer and microbial diseases.

Fifteen Inula spp. From these, only 7 involved extracts of the reported spp. Furthermore, 90 bioactive compounds were isolated from 16 Inula spp. The characteristic compounds of the genus, sesquiterpene lactones, are involved in a network of biological effects, and in consequence, the majority of the experimental studies are focused on these products, especially on their cytotoxic and anti-inflammatory activities. Although there are ca.

Eight of the sixteen Inula spp. Despite Inula royleana DC. Kerner are being used in traditional medicine, as far as we are aware, these species were not subjected to phytochemical or pharmacological studies.

The biological activities. Anatomy and Micromorphology of Inula helenium subsp. Full Text Available Inula helenium L. Grierson and Inula ensifolia L. The secretory cavities in the leaves and stem of both investigated taxa were located in the neighbourhood of the vascular bundles and in the rhizomes in the secondary cortex. The leaf mesophylls of investigated Inula taxa were homogeneous.

Stomata were anomocytic in two species. The distribution and density of the eglandular and glandular trichomes provide information of taxonomical significance. Moreover, the cypselas of I. Additionally, the number of ribs, the shape of carpopodium and stylopodium were diagnostic taxonomic characters between the two taxa.

For the first time the amino acid composition and raw protein of some species from Inula genus was determined Inula germanica, Inula ensifolia, Inula aspera, Inula orientalis, 16 amino acids were discovered, 7 of which were essential, and raw proteins which substantival composition amounted to Three new labdanes isolated from Eragrostis viscosa.

Sebastiao, N' Soki N. It was also studied the genotoxicity of E. Both assays were negative. Sebastiao, N'Soki N.

Chemistry and antifungal potential of Alantolides from Inula Alantolactone and isoalantolactone were isolated from powdered roots of Inula racemosa H. Soxhlet extraction followed by the column chromatography. Pyrazolines of alantolactone and isoalantolactone were synthesized using diazomethane, diazoethane and diazopropane.

The structure elucidation of the Thidiazuron-induced shoot organogenesis of Cleome viscosa L Feb 26, Shobana Rathi1, S. Bhuvaneshwari1, B.

Figure 1. Effect of MS basal medium strength a and and GA, b. Secondary Metabolites from Inula britannica L. Full Text Available Inula britannica L. Flowers or the aerial parts are a rich source of secondary metabolites. These consist mainly of terpenoids sesquiterpene lactones and dimmers, diterpenes and triterpenoids and flavonoids.

The isolated compounds have shown diverse biological activities: anticancer, antioxidant, anti-inflammatory, neuroprotective and hepatoprotective activities. This review provides information on isolated bioactive phytochemicals and pharmacological potentials of I.

Composite aster Inula L. Asteraceae: a new generic record for Nicobar Islands, India. Asteraceae represented by the species Inula cappa Buch.

Allelopatic Potential of Dittrichia viscosa L. Full Text Available Dittrichia viscosa L. Greuter is a pioneer species belonging to the Compositae family. It is widespread in the Mediterranean basin, where it is considered invasive. It is a source of secondary metabolites, playing an important ecological role. In the current study, the allelopathic potential of D. The VOCs effect was also studied on lettuce adult plants in microcosm systems, which better mimicked the open field conditions.

The VOCs composition revealed a large presence of terpenoids, responsible of the effects observed.


What Exactly is Inula Viscosa?

Colorectal cancer CRC is the second most common cancer in females and the third in males worldwide. Conventional therapy of CRC is limited by severe side effects and by the development of resistance. Therefore, additional therapies are needed in order to combat the problem of selectivity and drug resistance in CRC patients. Inula viscosa IV is a well-known medicinal perennial herb in traditional medicine. It is used for different therapeutic purposes, such as; topical anti-inflammatic, diuretic, hemostatic, antiseptic, antiphlogistic, and in the treatment of diabetes. Several studies attempted to reveal the anti-cancer activity of different extracts prepared by different organic solvents from different parts of the IV plant. The aim of the present study is to examine the potential beneficial effects of IV leaf aqueous extract on the growth of colon cancer cells in vitro and in vivo.


Control of Plant Diseases by Extracts of Inula Viscosa

The Inula Viscosa is quite a magical plant, which is why we Lavior use it in all of our skincare products. A diabetic will usually suffer from wounds that get infected all too easily, and the aim of using Inula Viscosa in our skincare products is to heal the wounds much faster and prevent infection. But what exactly is the Inula Viscosa? This plant has been highly regarded for thousands of years as one of the most effective medicinal plants in Israel, although it is not commonly heard of anywhere else. Many people outside of Israel have not heard of this plant, and so do not know the magical benefits it can offer for skin health and wound healing.


Inula viscosa L. Aiton sticky fleabane is popular medicinal plant in the family Asteraceae. It has been used in traditional medicine in the treatment of cancer, diabetes, hypertension, bronchitis, tuberculosis, wounds, skin diseases, infertility, lung and gastro-duodenal disorders. Aim of this study was to evaluate in vitro antiproliferative, antioxidant and antibacterial activities of aqueous and methanol extracts of aerial parts of I. Antioxidant activity was revealed by using 2,2-diphenylpicrylhydrazil DPPH method.

Related Articles